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细胞免疫应答的英文

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"细胞免疫应答"怎么读用"细胞免疫应答"造句

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  • cell-mediated immune response

例句与用法

  • The evidence for a significant role for cell-mediated immune responses in other protozoon diseases of animal is less complete .
    在动物的其它原虫性疾病中,有关细胞免疫应答的重要作用的证据尚不充足。
  • Cell immune response induced by hepatitis b virus dna vaccine in mice
    乙肝病毒核酸疫苗诱导小鼠细胞免疫应答的研究
  • Study on the cellular immune responses induced by p30 dna vaccine of toxoplasma gondii in mice
    疫苗免疫小鼠诱导细胞免疫应答的研究
  • Dendritic cells ( dc ) are the most potent professional antigen - presenting cells ( apc ) , required for the initiation of immune response . for all that the mechanism of dc functions are not fully elucidated
    树突状细胞( dendriticcell , dc )是一种重要的专职抗原提呈细胞( apc ) ,具有刺激初始型t细胞增殖、启动初次免疫应答的独特功能,是t细胞免疫应答的直接启动者和调控者。
  • Up to now , clinical trails have been conducted in u . s . a . and europe to observe the antitumor effects of exosomes . exosomes may be a kind of potential vaccines for tumors in future . on the other hand , exosomes may be a kind of tolerogenic materials
    为此,我们以一种c57bl / 6来源的3lllewis肺癌细胞系建立模型,用3ll细胞系和3ll肿瘤组织分泌的exosomes进行了体内和体外的功能实验,并从t细胞免疫应答的角度初步探讨了其作用的机制。
  • At present , in an attempt to stimulate specific antitumor immunity , experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes . however , there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens . 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype , the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype , the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
    但是,学者们发现这一疗法存在着如下的缺陷:单一ctl表位抗原肽的应用其抗肿瘤作用弱于多种肿瘤抗原的联合应用,且有诱导免疫耐受的潜在危险,有时反而会促进肿瘤的生长;事先需对患者的hla单倍型进行鉴定,以确定ctl表位与hla单倍型是否匹配,目前尚缺乏能与所有hla单倍型相匹配的ctl表位,从而限制了这一疗法的应用;这一疗法所产生的ctl在体外能有效杀伤经肿瘤抗原肽共孵育过的靶细胞,但对肿瘤细胞的杀伤能力较弱:这种l表位抗原肽缺乏cd4汀h细胞相关的表位,因此,不能诱导有效的th细胞免疫应答
  • Dendritic cells are characterized by their ability to efficiently present antigen , and are uniquely equipped to stimulate naive t cell responses . immature dendritic cells acquire antigens from throughout the peripheral body , then migrate to t - lymphocyte - dependent areas of lymph nodes . thus , dendritic cells act as bridges , operating at the interface of innate and acquired immunity
    作为机体免疫系统中功能最强的专职性抗原提呈细胞( antigen - presentingcells , apc ) ,树突状细胞( dendriticcells , dc )能高效地摄取、加工处理和提呈抗原,具有较强的迁移能力,并能显著地激活初始型t细胞以启动t细胞免疫应答反应,此外, dc与b细胞以及nk细胞等也存在着相互作用,可见, dc在连接天然免疫和获得性免疫之间起着非常重要的作用。
  • Dcs play a pivotal role in the development of antitumor immunity . t lymphocytes immune response induced by direct antigen - pulsed dcs can not maintain longer for peptides - mhc department or mhc molecules degeneration . the method of dcs loading with tumor antigen gene is another potential approach to enhancing and maintaining immune response
    在用抗原直接刺激dc时,由于抗原- mhc复合物解离或细胞mhc分子降解而不能维持所诱导的t细胞免疫应答,借助载体把肿瘤抗原基因导入dc后肿瘤抗原在dc内的持续表达能增强其抗原提呈能力并能维持所诱导的免疫效应。
  • Objectives to improve the effect of a single mtb8 . 4 dna vaccine , we constructed a chimeric mtb8 . 4 / hil - 12 eukaryotic plasmid by linkage of mycobacterium tuberculosis mtb8 . 4 gene to human il12 gene with a simple linker ( gly4 - ser ) 3 . we analyzed the immunogenicity of chimeric dna vaccine and investigated the immune responses elicited when mtb8 . 4 / hil12 was presented as endogenous ag
    目的:以il - 12作为分子佐剂,与结核杆菌新抗原mtb8 . 4基因连接形成嵌合分子,将其克隆到真核表达质粒中,构建成嵌合dna疫苗,研究其在小鼠体内诱导细胞免疫应答的效果及对c57bl 6n小鼠的免疫保护作用,为寻求安全、有效、廉价的结核病新疫苗打下基础。
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