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大脑中动脉缺血的英文

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"大脑中动脉缺血"怎么读用"大脑中动脉缺血"造句

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  • mcao

例句与用法

  • To make clear the hypothesis , a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study , respectively . we first studied the cellular localization of kvl . 2 and the co - localization of kvl . 2 protein and vegf receptors flk - 1 and flt - 1 , observed the effect of mcao on kvl . 2 expression and phosphrylation in the rat brain in vivo , then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl . 2 in sh - sy5y cells . finally , in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl . 2 phosphorylation , we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl . 2 phosphorylation
    为了验证上述假设,本文分别在整体和离体水平,采用大脑中动脉缺血( middlecerebralarteryocclusion , mcao )和体外氧?糖剥夺( hypoxiaandglucose - deprivation , hgd )缺血模型,首先了解了kv1 . 2蛋白的细胞定位及与vegf受体flk - 1和flt - 1的共存情况,观察了整体mcao后缺血再灌不同时间大鼠脑内kv1 . 2蛋白的磷酸化水平变化,然后通过外源性给予vegf蛋白,在sh - sy5y细胞株上观察其对缺血细胞存活率及kv1 . 2蛋白磷酸化水平的影响,最后利用vegf反义脱氧寡核苷酸( oligodeoxynucleotide , odn )特异阻断内源性vegf蛋白的表达,观察内源性vegf蛋白在缺血细胞损伤及调节kv1 . 2蛋白磷酸化中的作用,以进一步明确vegf缺血保护效应与其调节kv1 . 2蛋白磷酸化之间的关系。
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