wwtr1造句

• WWTR1 It is a SMADs and has a key role in coupling them to the transcriptional machinery such as the mediator complex.
• BAG3 is able to stimulate the expression of cytoskeleton proteins in response to mechanical tension by activating the transcription regulators YAP1 and WWTR1.
• Using the human SHSY5Y cell line as a model of neuronal differentiation, human FAT1 was shown to regulate the nucleocytoplasmic relocation of WWTR1 / TAZ and enhanced transcription of the Hippo target gene CTGF . The same study also showed FAT1 was able to regulate TGF-beta signalling