tachykinin造句

• This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B.
• Studies show that in postmenopausal woman there is an increased expression of tachykinin neurons in the arcuate nucleus.
• This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
• The tachykinin family is characterized by a common C-terminal sequence, Aromatic or an Aliphatic amino acid.
• Tachykinin NK 1 receptor consists of 407 amino acid residues, and it has a molecular weight of 58.000.
• "' Tachykinin peptides "'are one of the largest families of neuropeptides, found from amphibians to mammals.
• There are three known mammalian "'tachykinin receptors "'termed NK 1, NK 2 and NK 3.
• The Neurokinin 3 receptor is a part of a larger family of G-protein coupled receptors that binds all tachykinin proteins.
• In addition, Substance P can bind to Tachykinin NK-1 receptors leading to increased intracellular calcium concentrations and subsequently increased saliva secretion.
• The two human tachykinin genes are called TAC1 and TAC3 for historical reasons, and are equivalent to Tac1 and Tac2 of the mouse, respectively.
• The different movements have been found to be altered by neuromodulators, including serotonin in a study by Harris-Warrick and Cohen in 1985 and tachykinin in a study by Parker et al . in 1998.
• NK 1 receptor, as well as the other tachykinin receptors, is made of seven hydrophobic transmembrane ( TM ) domains with three extracellular and three intracellular loops, an amino-terminus and a cytoplasmic carboxy-terminus.
• Tachykinin NK 1 receptor, often referred to as NK 1 receptor, is a member of family 1 ( rhodopsin-like ) of G protein-coupled receptors and binds to the Arg, which interacts with G-proteins.
• Causes of pre-eclampsia have been widely researched and the leading suspect in the investigation has always been the tachykinin peptide neurokinin B . During cases of pre-eclampsia, placental expression of the TAC3 gene, which codes for NKB, was found in high levels.
• Inflammation provides a protective immune response to such stresses may also result in progressive damage to the CNS . There is significant evidence to indicate that tachykinins are a major component of the neural inflammatory response at peripheral tissues as well as the CNS . The ability to regulate tachykinin secreation represents an important mechanism for designing potentially useful drugs to treat inflammation.
• Like all tachykinin peptides, Eledoisin shares the same consensus C-terminal sequence, that is, Phe-Xxx-Gly-Leu-Met-NH . The invariant " Phe7 " residue is probably required for receptor binding . " Xxx " is either an aromatic ( phenylalanine, tyrosine ) or a branched aliphatic ( valine, isoleucine ) side chain and is thought to be important in receptor selectivity.