deoxyribonucleoside造句

• This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine.
• Ribonucleoside diphosphate ( NDP ) is reduced by thioredoxin to a deoxyribonucleoside diphosphate ( dNTP ).
• Because TK2 plays a key role in the mitochondrial salvage pathways of several deoxyribonucleoside triphosphates ( dNTPs ), a lowered activity would lead to less cycling of nucleotides.
• It is the ribonucleoside triphosphate of thymidine, but the nomenclature with " 5-methyluridine " is used because the term thymidine triphosphate is used for the deoxyribonucleoside by convention.
• It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2'position . 5-Methyluridine contains a thymine base joined to a ribose pentose sugar.
• For example, enzyme deoxyribonucleoside triphosphate pyrophosphatase, encoded by YJR069C in " S . cerevisiae " and exhibiting ( d ) ITPase and ( d ) XTPase activities, hydrolyses dXMP, respectively.
• The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in " S . cerevisiae " and containing ( d ) ITPase and ( d ) XTPase activities, hydrolyses dITP releasing pyrophosphate and dIMP.
• Catalysis of ribonucleoside 5-diphosphates ( NDPs ) involves a reduction at the 2-carbon of ribose 5-phosphate to form the 2-deoxy derivative-reduced 2-deoxyribonucleoside 5-diphosphates ( dNDPs ).
• More specifically some of its important reactions include treatments with 2'- deoxyribonucleoside phosphorylase, methyltransferase, or nucleoside phosphorylase, affording the corresponding 5'- phosphate, giving rise to no methylation at its 5-position, or no cleavage of the glycosyl bond in contrast to 5-fluoro-2'- deoxyuridine, respectively.
• The absence of the 3'- hydroxyl group means that, after being added by a DNA polymerase to a growing nucleotide chain, no further nucleotides can be added as no phosphodiester bond can be created based on the fact that deoxyribonucleoside triphosphates ( which are the building blocks of DNA ) allow DNA chain synthesis to occur through a condensation reaction between the 5'phosphate ( following the cleavage of pyrophospate ) of the current nucleotide with the 3'hydroxyl group of the previous nucleotide.
• Some examples include developing ( a ) a continuous protocol for the two-carbon homologation of esters to prepare ( a ) ?-unsaturated esters with high yield and selectivity; ( b ) 2-functionalized phenols via benzyne-mediated in-line generation of arylmagnesium intermediates and aerobic oxidation; ( c ) developing a three-step continuous flow system which integrates in-line isocyanide formation and photochemical cyclization for preparing quinoxaline derivatives and ( d ) a two-step glycosylation and deprotection sequence to prepare 5-deoxyribonucleoside pharmaceuticals.