cxxc造句

• PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif.
• AGR2 is a protein disulfide isomerase, with CXXC active domain motifs for oxidation and reduction reactions.
• :In many eukaryotes, the KDM2A protein contains a CXXC zinc finger domain capable of binding unmethylated CpG islands.
• All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity.
• Like other thioredoxin-based enzymes, DsbA's catalytic site is a CXXC motif ( CPHC in " E . coli"
• Some tetraspanins can have N-linked glycosylations on the long extracellular loop ( LEL, EC2 ) and palmitoylations at a CXXC motif in their transmembrane region.
• The two subunits form a heterodimer and are likely linked by a disulfide bond between two conserved cysteine rich motifs : CXXC in SU and CX 6 CC in TM.
• This dithiol then donates electrons to the periplasmic C-terminal thioredoxin motif ( CXXC ) of DsbD, thereby reducing C461 and C464 ( C6 and C7, respectively ).
• Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich ( CXXC ) domains, and some differences in the COOH terminus.
• It has recently been demonstrated that a ZF-CxxC DNA binding domain within FBXL11 / KDM2A has the capacity to interact with non-methylated DNA and this domain targets FBXL11 / KDM2A to CpG island regions of the genome where it specifically removes histone H3 lysine 36 methylation.