acrosin造句

• The importance of acrosin in the acrosome reaction has been contested.
• Acrosin digests the zona pellucida and membrane of the oocyte.
• Acrosin is the major proteinase present in the acrosome of mature spermatozoa.
• This suggests the further role of acrosin inhibitors as potentially viable agents in the prevention of HIV transmission.
• After this reaction occurs, the zymogen form of the protease is then processed into its active form, ?-acrosin.
• Under the secondary binding protein hypothesis, acrosin could serve a role in binding to molecules on the zona pellucida, tethering the spermatozoa to the egg.
• It has been found through genetic knockout experiments that mouse spermatozoa lacking ?-acrosin ( the active protease ) still have the ability to penetrate the zona pellucida.
• :Maybe the user is looking for specific information, along the lines of this : Effect of abstinence on sperm acrosin, hypoosmotic swelling, and other semen variables.
• This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix.
• The S1 pocket regulates Acrosin's specificity for Arg and Lys substrates, with a conserved Trp-215 serving as a " gatekeeper " residue for the binding site entrance.
• Deficiency of protein C in inhibitor in human body may cause male infertility . Protein C inhibitor has a great role in reproduction as it has ability to inhibit the sperm protease acrosin.
• The first stage is the penetration of corona radiata, by releasing hyaluronidase from the acrosome to digest cumulus cells surrounding the oocyte and exposing acrosin attached to the inner membrane of the sperm.
• Moreover, as serine proteases are important in the potentiation of HIV, research has found that an acrosin inhibitor, 4'- acetamidophenyl 4-guanidinobenzoate, possess the ability to inhibit HIV infection in virus-inoculated lymphocytes.
• LeftAn important structural element of ?-acrosin is a highly charged patch ( formed through both amino acids and post-translational modifications ) on its surface region, that has been termed the " anion binding exosite . " This structural feature is consistent with the secondary binding protein hypothesis, as charge-charge interactions would stabilize a protein-zona pellucida " tethering " complex.