He was ruined past hope now; his destruction would be immediate and sure, and he would be an outcast and friendless . 现在他是一败涂地，毫无希望了；他已经注定了马上就要完蛋，成为一个无家可归，无亲无友的可怜虫。
"the fact is, life isn't much a fit for either of us," winsett had once said, "i'm down and out; nothing to be done about it. " “事实是，我们俩对生活都不大适应，”温塞特曾经这么说过。”“我是不行了，完了，毫无希望了。”
The ship was sinking , all hopes deserted them 船在下沉中，他们毫无希望了。
The ship was sinking ; all hopes deserted them 船在下沉中,他们毫无希望了。
A hopeless future seemed to spread out before her 展现在她面前的似乎是毫无希望的前途。
Getting up every morning , feeling hopeless , 每天醒来，觉得毫无希望
Our position is hopeless ; we ' ll never get out alive 我们的处境毫无希望,我们决不可能活着出去。
The patient seems hopeless of recovery 那个病人毫无希望复元。
It ' s finished . it ' s gone , dead 就结束了，灰飞烟灭，毫无希望
Our position is hopeless ; we will never get out alive 我们的境遇已经毫无希望，我们决不会活著出去。
