Within the family of angiogenesis inhibitors , angiostatin , an endothelial cell - specific inhibitor , has been demonstrated to be the most potent 在血管生成抑制因子的家族中血管抑素( angiostatin )作为内皮细胞特异性的抑制剂已显示出强大的作用。
The target of endostatin is endothelia of the blood vessel , inhibiting the endothelial cell proliferation and migration , demonstrating an intense angiogenic activity 实验发现内皮抑素直接作用于血管内皮细胞，抑制血管内皮细胞增殖、迁移，具有强烈抑制血管生成活性。
And afp - ir cells appeared in the outer membrane of liver or blood vessel endothelial neared the outer membrane only on 55th day . ss , 5 - ht , glu , pp , sp , egf and afp were not expressed in all liver cells 各期肝细胞均未发现表达胰高血糖素、胰多肽、生长抑素、 5 -羟色胺、 p物质、表皮生长因子、甲胎蛋白。
Results the secretion of gastric antrum mucosa growth inhibition is significantly more in the cases with sthenia - syndrome than in the cases with asthenia - syndrome and the control group 结果以实证为主的胃脘痛患者血清、胃窦黏膜生长抑素的分泌量显著高于虚证患者及对照组，胃阴不足和脾胃虚窦型则明显下降。
The first part of our experiment is to extract and purify the total rna from the human liver tissue in the condition without rnase and to identify its integrity and purity 本研究第一部分包括肝组织中总rna的分离提取； rt - pcr扩增出血管抑素基因。首先，采集术后新鲜肝组织，并于无rnase的条件下分离纯化总rna 。
The purpose of my work was to clone and express of mouse endostatin gene , we construct a temperature - sensitive expression system : pbv220 - endostatin . the main work was as following : 1 本文进行小鼠内皮抑素基因的克隆及表达，基因工程方法构建了鼠内皮抑素的温敏型表达载体pbv220 - endostatin ，为此作了以下工作： 1
Angiostatin ( as ) is a kind of polypeptide identified as a product of plasminogen cleavaged by protease . it blocks neovascularization by directly inhibiting endothelial cell proliferation and migration 血管抑素( angiostatin ， as )是血浆纤溶酶原( plasminogen ， plg )经蛋白水解酶降解生成的多肽片段，是直接作用于血管内皮细胞的血管生成抑制剂。
Some researches showed that inhibitory effect of human angiostatin ( kl - 3 ) on angiogenesis was stronger than that of human angiostatin ( kl - 4 ) , and kringle4 of plasminogen had no direct action on inhibition of angiogenesis 研究表明血管抑素( k1 - 3 )抑制内皮细胞增殖的能力强于血管抑素( k1 - 4 ) ，第4个环饼状结构域对抑制内皮细胞的增殖没有直接的关系。
Angiostatin , a multiple kringle ( 1 - 4 ) - containing fragment of plasminogen , is an effective natural inhibitor of tumor angiogenesis , which is a potent inhibitor of angiogenesis in vivo , and selectively inhibits endothelial cell proliferation and migration in vitro 血管抑素angiostatin是纤溶酶原的内源片段，包括四个kringle结构，是一种重要的内源性新生血管生成抑制剂。
Somatostatin can decrease the secretion of digest fluid so as to alleviate the abdomen distention ; it can much more efficienctly prevent the bowel bacteria immigration and peritonitis that to give the antibiotic agents via venous and gastric tube simultaneously 应用生长抑素可抑制消化液的生成，减轻腹胀；同时经静脉和肠道内给于抗菌药物能更好地防治肠道细菌移位和腹腔内感染。
