dahp中文是什么意思

• 羟基嘧啶

• "dahqan" 中文翻译 :    达赫甘
• "dahoukou pere" 中文翻译 :    达胡库佩雷
• "dahr" 中文翻译 :    达尔; 达赫尔
• "dahouet" 中文翻译 :    达乌埃
• "dahr al baydar" 中文翻译 :    代赫尔拜德尔
• "dahoue" 中文翻译 :    达惠
• "dahr al injas" 中文翻译 :    因贾斯山
• "dahou" 中文翻译 :    达胡
• "dahr al qadib" 中文翻译 :    盖迪卜山
• "dahotre" 中文翻译 :    达霍特雷

• In microorganisms and plants the first step in the aromatic acid biosynthetic pathway is the condensation of pep and e4p , with the release of the phosphate of pep and the formation of dahp
  在细菌和植物中，由公共途径莽草酸途径以及三个专一性途径分别合成苯丙氨酸、酪氨酸和色氨酸三种芳香族氨基酸。
• This reaction is catalyzed by dahp synthase , which in microorganisms is also the target for negative - feedback regulation of the pathway mediated either by the pathway intermediate chorismate , or by endproducts phenylalanine , tyrosine and tryptophan
  在大肠杆菌中， arog基因编码受苯丙氨酸反馈抑制的dahp合成酶同工酶arog ，催化e4p和pep反应生成dahp 。
• In bacterial , many enzymes compete for intracellular pep , especially the phosphotransferase system which is responsible for glucose transport in e . coli . this system uses pep as a phosphate donor and converts it to pyruvate , which is less likely to recycle back to pep
  Pep和e4p是dahp合成的限制性底物，在大肠杆菌中， pep又是许多酶的竞争性底物，特别是负责葡萄糖转运的糖磷酸基转运系统。
• When both genes were co - expressed in e . coli , the activity of ppsa varied from 2 . 1 - 9 . 1 fold comparing to control , but the activity of tkta was relatively stable ( 3 . 9 - 4 . 5 fold ) . whatever the two genes were expressed respectively or cooperatively , both could promote the production of dahp , the first intermediate of the common aromatic pathway , but co - expression was more effective on forming dahp and screened ppt - and ptp - as more effective . the results demonstrate that co - expression of ppsa and tkta can improve the production of dahp , and what ' s more , when multigenes co - expressed , the recombinant which has coordinated enzymes activity is optimum
  莽草酸途径的最优化和整体调控基因csra的敲除正是上述改变的分子基础，同时也为三种芳香族氨基酸的基因工程菌的构建打下了基础; 7 .在国内外首次实现了共同途径限制性底物关键酶ppsa刁无‘及arog与分支途径关键酶基因phea的串联高效表达，所构建的重组质粒ptga ，其ppsa 、 tkta 、 arog 、 cm和pd的酶活分别比对照提高了3 、 2 、 2 ， 5 、 4 、 2 . 3倍，且其酶活比较协调一致; 8 .将ptga导入到筛选的基因敲除和基因替换菌株大肠杆菌31884 c甲b中，摇瓶发酵证实比以往所构建的基因工程菌株具有较高的phe产量和糖转化率率，分别为0 . 448 %和22 . 4 % 。
• So it has increasing commercial demand . escherichia coli and many other microoganism synthesize aromatic amino acids through the condensation reaction between phosphoenolpyru vate ( pep ) and erythrose - 4 - phosphate ( e4p ) to form 3 - deoxy - d - arabinohep tulosonate 7 - phosphate ( dahp ) . pep and e4p are limiting substrates for formation of dahp
  大肠杆菌和许多微生物一样，其合成芳香族氨基酸的起始物是由磷酸烯醇式丙酮酸( pep )和4 -磷酸赤癣糖( e4p )二者缩合形成的3 -脱氧- -阿拉伯庚酮糖酸- 7 -磷酸( dahp ) 。
• The common biosynthesis pathway of aromatic amino acids includes seven steps from dahp to chorismate acid . for the common pathway , 3 - dehydroquinate ( dhq ) synthase ( encoded by arob ) , 5 - enolpyruv - oylshikimate s - phosphate ( epsp ) synthase ( encoded by aroa ) , and chorisma - te synthase ( encoded by aroc ] are rate - limiting enzymes
  芳香族氨基酸的合成步骤有七步是共同的，亦即从dahp到分支酸的合成步骤，其中脱氢奎宁酸合成酶( arob ) 、 5 -烯醇式丙酮酰莽草酸合成酶( aroa )和分支酸合成酶( aroc )是此代谢途径的关键酶。