In cases of bacterial or fungal infections , treatment may include oral antibiotics or topical antimicrobial cream to treat the infection . other ointment may be used to ease skin irritation , if necessary 口服或外用的抗生素，主要用于治疗由细菌或霉菌感染引起的龟头炎。若龟头炎是由于皮肤受化学物品刺激而引起，就要避免再接触有关的化学物品。
