Protein kinase b is newly found as a serine / threonine protein kinase , it could have widely spread functions in cell cycle regulation . the activation of protein kinase b / akt is thought to be a critical step in the phosphoinositide 3 - kinase pathway which regulates cell growth and differentiation 蛋白激酶c ( proteinkinasec ， pkc )和蛋白激酶b ( proteinkinaseb ， pkb )同属于丝苏氨酸蛋白激酶，广泛参与细胞的多种生命过程，包括生长、分化、细胞周期调控、细胞凋亡等。
Protein kinase a is camp - dependent kinase , one of the most important signal transduction pathways , plays a pivotal role in growth , differentiation , tumor occur , cell cycle control , etc . pka activators such as camp , 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes , also in xenopus oocytes 蛋白激酶a ( proteinkinasea ， pka )是依赖于camp的丝苏氨酸蛋白激酶，是重要的信号传导途径之一，广泛参与许多生命过程，包括生长、分化、肿瘤发生、细胞凋亡、细胞周期调控等。以小鼠卵母细胞为实验对象，给予pka激动剂camp 、 8 - br - camp或磷酸二酯酶抑制剂imbx ( isomethylbutylxanthine )均可抑制小鼠卵母细胞的胚泡破裂及减数分裂成熟。
