The long - term domestication of liquor - making microbes under the unique liquor - making environment of maotai liquor ( high temperature starter - making , high temperature stacking fermentation , and high temperature anaerobic fermentation etc . ) and the succession of microbial groups through heredity , mutation , growth and derivation etc . had accumulated abundant high temperature resistant , high acid resistant and high alcoholicity resistant extreme microbes 摘要茅台酒独特的极端高温制曲、高温堆积发酵、高温厌氧发酵等酿酒环境长期对酿酒微生物进行驯化,各种微生物经过遗传、变异、消长和衍化等微生物群落的演替,促成了酿酒微生态环境中丰富的耐高温、耐高酸和耐高酒度等极端微生物的富集。