Levels of fasting blood glucose and 24h urinary microcontent of albumin 24 h malb were determined dynamically ; the serum glycosyl hemoglobin hba1c was determined after the last medication ; the ultrastructural changes of kidney were observed by transmission electron microscope ; the expressions of collagen , fibronctin , laminin ln , and the ecm metabolism influencing factors , including mmp2 , tissue inhibitor of metalloproteinase timp2 , transfer growth factor 1 tgf 1 in renal tissue were detected by immunohistological chemistry and image collecting analytical system 动态检测各组大鼠空腹血糖fbg 24h尿微量白蛋白24h malb ，末次给药后测定大鼠血浆糖化血红蛋白hba1c透射电镜观察各组大鼠肾脏超微结构改变，应用免疫组化技术及图像采集分析系统测定各组大鼠肾脏组织中型胶原c纤维连接蛋白fn层粘连蛋白ln的表达，测定影响ecm代谢的基质金属蛋白酶2 mmp2基质金属蛋白酶抑制剂2 timp2及转化生长因子1 tgf 1的表达。
Intravenous medication pumps allow the nursing staff to titrate medications ; foley catheters and urine collection bags aid in monitoring urine output ; sequential compression devices squeeze the lower extremities and reduce the incidence of deep venous thrombosis ; transvenous pacemakers stimulate the patient ' s heart to beat ; dialysis machines remove fluid and correct electrolyte and acid - base disturbances ; intraaortic balloon pumps assist the heart ' s contractility ; and neurologic monitoring systems measure intracranial pressure 静脉内给药泵由普通护士用于滴定药物；弗利氏导管和集尿袋帮助监测排尿量；连续压迫装置挤压下肢，减少深部静脉血栓形成；经静脉起搏器刺激病人心脏跳动；透析仪除去液体，纠正电解质和酸碱紊乱；主动脉内气囊泵支持心脏收缩；神经病学监测系统测定颅内压。
Poiycyclic aromatic hydrocarbons ( pah ) are priority trace organic pollutants in the clrtap ( convention on long - range transboundary air poliution ) pops ( persistent organic poilutants ) protocol . both laboratory experiments and fie1d surveys unequivocally demonstrated that pah adversely affect estuarine and marine organisms . pah are implicated in the development of iesions and tumors in fish , they produce biochemical disruptions and cell damage that iead to mutations , developmental malformations and cancel although many marine organisms do not exhibit acute responses to pah " exposure , but suffer sublethal effects 本论文以湄洲湾海域和厦门西海域养殖区为研究区域，采用现代分析技术，从分子水平上系统研究了多环芳烃( pah )在海水、沉积物、养殖鱼类中的含量分布：通过现场实验，实验室暂养、投毒和恢复实验系统测定了养殖鱼类的肝脏、胆汁、鳃、全血等不同器官、组织的生化指标及养殖鱼类肝脏、胆汁的化学指标，探讨了这些指标对水环境多环芳烃污染的生物指示作用。
