Mccormack d g . calcitonin gene - related peptide vasodilation of human pulmonary vessels . j appl physiol , 1989 , 67 : 1265 尚云晓,袁壮,赵淑琴,等.哮喘患儿血浆降钙素基因相关肽与内皮素水平相关研究.中国实用儿科杂志, 1996 , 11 ( 3 ) : 146
Effects of calcitonin gene - related peptide and nerve growth factor on spatial learning and memory abilities of rats following focal cerebral ischemic - referfusion 降钙素基因相关肽和神经生长因子对局灶性脑缺血再灌注大鼠空间学习记忆能力的影响
Botulinum toxin type a for modulating calcitonin gene - related peptide contents in jugular plasma and brain stem of migraine model rats triggered by nitroglycerin 型肉毒毒素对硝酸甘油引发偏头痛大鼠颈静脉血和脑干内降钙素基因相关肽水平的调节
Clinical significance of dynamic changes of plasma neuron - specific enolase , endothelin and calcitonin gene - related peptide in elderly patients with acute cerebral infarction 老年急性脑梗死患者血浆神经元特异性烯醇酶内皮素降钙素基因相关肽的变化
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This study is aimed to investigate the modulation of glu on synthesis of ps and illustrate the biological significance of glu and its receptor in lung in order to offer new ideas for the prevention and treatment of pulmonary diseases 本研究旨在观察glu对成年大鼠肺表面活性物质( ps )脂质合成的影响，以及降钙素基因相关肽( cgrp )对该效应的影响。以探讨肺内glu和glu受体的生物学意义，为临床肺部疾病的防治提供新的思路。
3 . calcitonin gene - related peptide attenuates glutamate - induced inhibition of pulmonary surfactant lipid synthesis ( d cgrp could reverse the decrease of [ 3h ] - choline incorporation induced by glu with dose - dependence ; ( 2 ) cgrp could block the decrease of the content of cct a mrna induced by glu in lung tissue ; ( 3 } cgrp could reduce the impairment of the ultrastructure of at ii cells induced by glu ; ( 4 ) cgrp could reverse the increase of mda content and decrease of sod level induced by glu in cultured lung explants , respectively ; ? grp had no significant effect on nos activity and increase of no production induced by glu 降钙素基因相关肽减轻谷氨酸所致肺表面活性物质脂质合成抑制的保护作用降钙素基因相关肽grp ）可显著减轻0所致肺组织h一胆碱掺入pc量的降低，并且呈剂量依赖保护效应； cgrp可逆转gill所致cctqinrna含量的降低； cgrp可减轻o所致肺11上皮细胞超微结构的损伤； cgrp可逆转o所致肺组织匀浆中mda含量增多、 sod水平降低的效应，并可逆转q所致肺组织ldh释放增多的效应； cg贩对gill引起的nos活性和no含量的升高均没有显著性影响。
Moreover , human ghrelin receptor exhibits a remarkable 50 % overall identity with human motilin receptor , therefore it was named as " raotilin - related peptide " . anatomical evidence showed that there are ascending and descending neuronal projections between pvn , bma and lower brain stem ( nts , dmx ) , which participate in the regulation of gastric acid secretion and gastrointestinal motility . moreover , pvn is the center of appetite regulatory web Pvn与低位脑干(延髓迷走复合体)及边缘系统之间有密切的纤维联系，且含有多种神经肽，参与胃酸分泌，胃肠活动等多种生理机能的调节，是影响消化道功能与摄食行为的重要中枢部分， pvn内胃动素可促进胃排空和摄食，而新发现的ghrelin /胃动素相关肽是否参与此核区对胃运动的调节机制及其可能的神经通路尚不明了。
It was recognized as a brain - gut peptide since the peptide and its receptor exist in the central nervous system . previously , we demonstrated that motilin and motilides activates cells in paraventricular nuclei ( pvn ) reflected by increased gastric motility and induction of the immediate early gene c - fos in conscious rat , which suggests central motilin participates in the regulation of gastric motility . it was reported in 2001 that ghrelin is an appetite - stimu latory signal from stomach with structural resemblance to motilin 胃动素( motilin ， mt )是由小肠上段粘膜内分泌细胞合成并分泌的22个氨基酸组成的脑肠肽，调节消化间期胃运动， pvn内给予胃动素和胃动内酯( motilides )可增强清醒大鼠胃运动，中枢微量注射胃动素可诱导pvn中立即早期基因c - fos的表达，提示中枢胃动素参与胃运动的调控，人ghrelin和胃动素之间有36的相似性，而且二者的受体之间有50的相似性，因而有人称ghrelin为“胃动素相关肽” 。
