Underlying chromosomal abnormalities , such as trisomy 13 , or maternal diabetes mellitus are possible causes , but some cases are sporadic 潜在的染色体异常,例如三倍体13 ，或母亲的糖尿病也是可能的原因。
Anencephaly is a form of neural tube defect that is typically an isolated birth defect that is not related to chromosomal abnormalities 无脑儿是神经管缺陷的一种类型，是单纯性先天性缺陷，与染色体异常无关。
An abnormality of chromosomes long associated with diseases of aging has , for the first time , been linked to colon cancer in people 50 years old and younger , an age group usually considered young for this disease 染色体异常经常被认为与老年病相关，然而首次被提出和50岁以下的年轻结肠癌患者相关。
This happens in normal pubertal stage , but can also be caused by diseases like testicular or brain tumours , liver diseases , thyroid gland hyperactivity , certain chromosome abnormalities and side - effects of some drugs ，也可由睾丸或脑肿瘤、肝病变、甲状腺亢奋、某些染色体异常、或某些药物等引致。
Ronnie , who was almost 15 when his family moved to california , was born with down s syndrome , a form of mental disability that affects his development so that his mental age is around six 当他们搬到加州时，罗尼已将近十五岁了，他出生时就患有唐氏症，这是一种染色体异常的病症，会造成智能障碍及生长迟缓的问题，因此，罗尼的心智年只有六岁而已。
Staining techniques which demonstrate structural transverse banding patterns are revealing less gross abnormalities and variations in chromosomes and proving valuable in relating normal and abnormal genes to particular sites on individual chromosomes ( gene mapping ) 显示染色体结构横带构型的染色体技术可显示较不明显的染色体异常和变异，并证明在说明正常和异常基因与各个染色体特殊位置之间的关系（绘制基因图方面）是有价值的。
Conclusion the results of present study indicated that chromosome abnormality is one of the frequent genetic causes for male infertility , suggesting that it is essential to screen chromosome abnormality during diagnosis of male infertility as well as before in vitro assisted fertilization by intracytoplamic injection 结论染色体异常是男性不育的一个常见遗传病因，在男性不育的诊断和卵细胞浆内单精子注射受精治疗前，对染色体的异常进行筛查十分必要。
