In conclusion , the results of checking of physiochemistry items , uv spectrum data , chromatographic fingerprints test and safty evaluation indicated that gpif avivity evaluation samples were eligible . through the comparison of methods for evaluating immunobiologic activity and the choosing of optimum methods to evaluating immunobiologic activity , we created assay methods evaluating immunobiologic activity for quality standard of gpif . the research of dose - effect of gpif can also supply theoretical materials for pharmacology . that the experiments on the factors which affect the immunobiologic activity of gpif and the comparison with similar drugs demonstrated that gpif was a kind of cellar immunoregulating drug with stable and high immunobiologic activity 综上所述，通过对gpif免疫生物活性评价实验样品材料的准备，显示由该工艺制备的实验样品材料理化性质稳定，活性成分含量充足，安全可靠，可以用来作为gpif免疫生物活性的评价;通过对gpif免疫生物活性评价方法的比较筛选及评价方法的优化，为gpif质量标准建立了较优免疫生物活性评价手段;同时gpif免疫生物活性剂量效应的发现，为该产品的免疫生物活性深入研究奠定了基础，也为gpif药效学研究提供了理论资料;对gpif免疫生物活性影响因素的探讨及与同类药品免疫生物活性的对比，证实gpif是一种免疫生物活性稳定、且具有高免疫生物活性的细胞免疫增强剂;同时，本研究也为同类产品免疫生物活性评价提供了方法学参考。
Abstract : an imidazole - catalyzed acylation method of phthalic anhydride is applied to the determination of hydroxyl values of reinforcing agent is211 . the analytical error is 5 . 0 10 - 3 . the relative standard deviation of the method is less than 0 . 04 and its coefficient of variation is not more than 5 . 0 10 - 3 . hydroxyl values determined in different batch samples meet the design requirement completely . this method is rapid and simple , it is adaptable to conventional analysis 文摘:以咪唑催化邻苯二甲酸酐酰化的方法测定增强剂is211的羟值，准确度高，分析误差为5 . 0 10 - 3 ；方法精密度好，标准偏差小于0 . 4 ，变异系数不大于5 . 0 10 - 3 ，测定不同批号试样的羟值完全符合商标值，方法快速、简便，适用于常规分析。
