Taxol is a kind of specific medicine to cure cancer , and microbial fermentation is an effective method to produce taxol . rapd techniques were used to analyze the genetic differences of four taxol - producing strains , and once more to classify and identify further from molecular level . these will provide abundant and reliable molecular markers for gene location and molecular cloning in the coming genetic engineering breeding of the strains 紫杉醇是一种用于癌症治疗的特效药物,微生物发酵法是生产紫杉醇的有效方法,采用rapd技术对4株紫杉醇产生菌的遗传差异进行分析,重新从分子水平对其进行了进一步的分类鉴定;并将为下一步的基因工程育种工作中的基因定位和分子克隆提供丰富可靠的分子标记。
This article reviews the clinical manifestations , mutation feature , gene location and phenotype of different ischemic cerebrovascular disease caused by monogenic disorders , including coagulation disorders , erythrocytic disorders , inherited small vessel disease , metabolic disorders , connective tissue diseases , vasculopathies and disorders of unknown etiology 本文主要阐述了单基因遗传障碍引起的缺血性脑血管病,包括凝血障碍、血细胞病、遗传性小血管病、代谢障碍、结缔组织病、大动脉病及不明原因引起缺血性脑血管病的临床特征、突变特点、基因定位及表型等遗传学研究进展。
