Influence of cryopreservation time on the expression of graft inducible nitric oxide synthase after orthotopic liver transplantation in rats 冷保存时间对大鼠原位肝移植后移植物诱导型一氧化氮合酶表达的影响
Methods eighteen patients who underwent the reconstruction of hepatic artery in olt during more than one year recently were collected and analyzed retrospectively 方法回顾性分析我院近一年来所施行18例原位肝移植术中肝动脉重建方式和技巧。
Yan ln , wang w , li b , et al . single - dose daclizumab induction therapy in patients with liver transplantation . world j gastroenterol , 2003 , 9 : 1881 文天夫,严律南,邓承琪,等.重度肝硬变患者行同种原位肝移植术后凝血障碍的诊断与治疗.中国普外基础与临床杂志, 2000 , 7 : 235 - 237
By using color doppler ultrasonography and blood cell counter , the recovery of blood cell counts and hypersplenism in 2 patients , undergoing orthotopic liver transplantation , who were diagnosed having hepatocirrhosis with portal vein hypertension and congestive splenomegaly before the transplantation were clinically observed 采用全血细胞计数监测和彩色多普勒超声断层的方法对两例因肝硬化合并门脉高压脾功能亢进而行同种异体原位肝移植术的患者进行了临床观察。
2 . rat orthotopic liver trarlsplantation was performed in the strong rejecter combination of bn ( rtl " ) to lew ( rtl l ) . this al1ogenic rejection model was stable and the survival time without immunosuppression agents was less than three weeks ( the average survival time was l 6 . 6 i 2 . 5 days , n = 5 ) 建立了大鼠bn ( rt1 ~ n ) lew ( rt1 ~ l )原位肝移植同种异体排斥模型,该模博士学位论义基因转移hu la个ig诱导大鼠移植肝免疫耐受的实验研究中文摘要型排斥反应时间较为恒定,在不应用免疫抑制剂的情况下,生存期3周(平均生存时问人66士2
Objective : to investigate the effect of pumpless portosystemic bypass in clinical piggyback liver transplantation . methods : after catheterized inferior mesenteric vein , the silastic catheter ( filled with heparin saline ) was connected with the catheterized tube of internal jugular vein or subclavian vein in four piggyback liver transplantation patients . the channel was opened after the portal vein was occluded . the portal vein blood poured into the superior vena cava through the pumpless channel . the changes of mesenteric congestion , portal vein pressure , blood pressure and pulse were observed . results : during the occlusion of portal vein , the portal vein pressure was increased greatly , the intestine was congested and swelled obviously and the blood pressure and pulse fluctuated gently . after the pumpless bypass opened , intestinal congestion and swell were abated markedly , the portal pressure , blood pressure and pulse gradually returned to normal range . conclusions : pumpless portosystemic bypass shows a great effect on clinical piggyback liver transplantation . it is a feasible and economical method 目的探讨背驼式原位肝移植术中采用体外门-体静脉无泵转流的临床效果.方法4例行背驼式原位肝移植患者,肠系膜下静脉属支插管经体外硅胶管(充满肝素盐水)与颈内静脉或锁骨下静脉插管相接,在阻断门静脉后开通肠系膜下静脉插管,门静脉血从体外无泵转流管流入上腔静脉,观察转流前后肠道瘀血、门静脉压、血压、脉搏等变化情况.结果门静脉阻断后肠道明显瘀血、肿胀,门静脉压力明显升高,血压、脉搏有不同程度的波动,无泵门静脉转流开放后,肠道瘀血、肿胀明显好转,门静脉压力逐渐恢复正常水平,血压、脉搏恢复正常.结论背驼式原位肝移植术中体外门-体静脉无泵流具有方便、经济、实用等优点,具有良好的临床效果