In the april s issue arteriosclerosis thrombosis and vascular biology , published by the american heart association , professor woo found that in 228 healthy subjects who have neither heart disease or diabetes but with " high normal " glycemia levels ( or with a number of components of metabolic syndrome ) , carotid intima - media thickening , an important marker for arteriosclerosis , was observed 胡教授在《动脉硬化、栓塞和血管生物杂志》 （ arteriosclerosis , thrombosis , vascularbiology ）的文章中指出：在228位尚未发现有心血管疾病亦未诊断为糖尿病患者的健康人中，血糖水平在正常界域但稍偏高（或兼有某些代谢综合症） ，其颈动脉内中膜厚度比其他正常人增厚，这是血管硬化病变的一个重要标示。
" endothelial vasodilator dysfunction and carotid intima - media thickening are the early markers of arteriosclerosis , " explained professor woo . " in adult obesity , there are many other risk factors such as hypertension and abnormality in lipids metabolism , it is very difficult to delineate the direct effect of obesity to vascular changes . however , it may be easier in children when we can avoid the interference of other risk factors and more precisely isolate the effect of obesity . 血管内皮功能障碍和颈动脉内中膜增厚是反映血管粥样硬化的早期指标；在成年人中，由于与肥胖并存高血压、脂肪代谢紊乱等多种因素的相互影响，很难评估肥胖对心血管粥样硬化性疾病的直接危害关系；在儿童时期进行检测，就可避开上述的多种其他因素的干扰，更准确地预测出单纯肥胖对血管硬化的影响。
Professor woo and professor sung stated in an article titled " overweight in children is associated with arterial endothelial dysfunction and intima - media thickening " in international journal of obesity that overweight , even of mild to moderate degree , in otherwise healthy children is independently associated with the development of vascular abnormalities 在《国际肥胖杂志》 （ internationaljournalofobesity ）上刊登题为儿童超重与内皮功能失调和内中膜增厚的关系一文中，胡教授和宋教授指出，正常儿童在生长期身体超重，甚至只是轻中度超重，都足以成为日后引发心血管疾病的另一新的危险因素。
