A wide variety of natural products , e . g . alkaloids , - lactames , biotin , amino sugars has been synthesized by 1 , 3 - dipolar cycloaddition reaction between nitrones and alkenes 摘要通过硝酮与烯烃化合物的1 ， 3 -偶极环加成反应合成了许多天然?物，如生物硷、 -内酰胺、生物素、氨基糖等。
Abstract : a wide variety of natural products , e . g . alkaloids , - lactames , biotin , amino sugars has been synthesized by 1 , 3 - dipolar cycloaddition reaction between nitrones and alkenes 文摘:通过硝酮与烯烃化合物的1 ， 3 -偶极环加成反应合成了许多天然产物，如生物碱、 -内酰胺、生物素、氨基糖等。
The paper reviews the recent progress in [ 3 + 2 ] cycloaddition using azomethine ylide , including preparation of ylide , mechanism and selectivity of reaction , and application in the total synthesis of natural products 摘要综述了亚甲胺叶立德的制备、它参与的[ 3 + 2 ]环加成反应的反应机理、反应选择性及在天然产物全合成中的应用等方面的最新进展。
The characterization of " click chemistry " ( the 1 , 3 - dipolar cycloaddition combined with the synthetic design of triazoles and tetrazoles ) is reviewed , and some recent examples of various bioconjugates synthesis are introduced based on the " click chemistry " 摘要介绍了利用1 , 3 -偶极环加成反应合成氮杂三唑和氮杂四唑的设计方法和反应特点，以及氮杂唑类化合物的合成在生物缀合物研究中的应用。
