Researchers were documenting that , for example , moderate to severe pain affects one in three patients being treated for cancer and between 60 and 90 percent of those with advanced disease 研究人员则开始收集证据，例如中度到重度的疼痛会影响1 / 3正接受癌症治疗的病患，以及60 ~ 90的末期患者。
Sudden changes of a mole , a wound that does not heal up , abnormal growths , severe itching and peeling of skin , severe pain etc . they may means serious illness like cancer and hence should not be ignored 例如痣突然产生变化伤口经久不愈合皮肤长出物体严重痕痒及脱皮剧痛等，都可能是严重疾病如皮肤癌的徵兆，不可忽视。
Indeed , in laboratory animals , such “ antagonists ” have been able to relieve the very severe pain caused by the acidic environment around tumors that have metastasized to and damaged bone tissue 的确，在实验动物身上，这类拮抗剂可消除由转移性骨癌（由他处转移至骨骼并使骨组织受损的恶性肿瘤）附近的酸性环境所引起的剧烈疼痛。
Sudden changes of a mole , a wound that does not heal up , abnormal growths , severe itching and peeling of skin , severe pain etc . they may means serious illness ( like cancer ) and hence should not be ignored 例如痣突然产生变化、伤口经久不愈合、皮肤长出物体、严重痕痒及脱皮、剧痛等，都可能是严重疾病(如皮肤癌)的徵兆，不可忽视。
News about him spread all over syria , and people brought to him all who were ill with various diseases , those suffering severe pain , the demon - possessed , those having seizures , and the paralyzed , and he healed them 24他的名声就传遍了叙利亚那里的人把一切害病的、就是害各样疾病、各样疼痛的、和被鬼附的、癫痫的、瘫痪的、都带了来、耶稣就治好了他们。
When i got out of a mobile restroom , i felt a severe pain on my leg and found that i had scratched it on an aluminum plate sticking out from the corner of the door . it hurt terribly , but after a while , the pain disappeared 那天，我从活动厕所出来时，大腿被门角处微翘的铝片刮了一下，当时感到一阵巨痛，可是过了一会后就没什么感觉了，因为裤子完好无损，我也就没当一回事，继续到大殿打坐。
For more severe pain , non - steroidal anti - inflammatory drugs which have both analgesics and anti - inflammatory actions may be used . there are many kinds but invariably they have side - effects which can include gastro - intestinal discomfort or even bleeding , renal failure , etc . therefore , they should be used with care and according to a doctor s advice 较强力的止痛药包括有消炎和止痛作用的非类固醇消炎止痛药，种类繁多，但都有不同程度的副作用，包括肠胃不适胃出血以致肾功能衰竭等，因此必须按医生的指示下使用。
For more severe pain , non - steroidal anti - inflammatory drugs which have both analgesics and anti - inflammatory actions may be used . there are many kinds but invariably they have side - effects which can include gastro - intestinal discomfort or even bleeding , renal failure , etc . therefore , they should be used with care and according to a doctor s advice 较强力的止痛药包括有消炎和止痛作用的(非类固醇)消炎止痛药，种类繁多，但都有不同程度的副作用，包括肠胃不适、胃出血、以致肾功能衰竭等，因此必须按医生的指示下使用。
When cataract reaches a very advanced stage , the affected eye may just be able to perceive hand motion or light . at this stage , which we describe as " hypermature cataract " , complications like glaucoma or acute inflammation may occur and will result in redness and severe pain of the eye . if no appropriate treatment is given , the eye may become blind 当白内障发展至"过熟期" ，而视力下降至只能感应到光线的地步，有可能导致如青光眼或过敏性葡萄膜炎等并发症的发生，眼睛会发红及感到非常疼痛，如病人得不到适当的治疗，会导致永远失明。
When cataract reaches a very advanced stage , the affected eye may just be able to perceive hand motion or light . at this stage , which we describe as " hypermature cataract " , complications like glaucoma or acute inflammation may occur and will result in redness and severe pain of the eye . if no appropriate treatment is given , the eye may become blind 当白内障发展至"过熟期" ，而视力下降至只能感应到光线的地步，有可能导致如青光眼或过敏性葡萄膜炎等并发症的发生，眼睛会发红及感到非常疼痛，如病人得不到适当的治疗，会导致永远失明。
