In order to investigate the relationship between myocardium responsiveness and its firing dynamic states , bilateral vagotomy , m receptor blocking , acetylcholine ( ach ) perfusion and continuously autonomic nerve ending stimulating methods were employed to change the rabbit sinoatrial node ( sa ) firing dynamics . isoprenaline , noradrenalin , ach , sympathetic or vagal nerve ending stimulation was used individually to measure the sa responsiveness in different dynamic state 3 、窦房结在正常放电状态时，对0卫， 0人0石ug kg异丙肾上腺素的反应性均强于应用阿托品后，前后相比有显著差异（ p 0刀5 ） ；待阿托品作用部分消除后，窦房结对异丙肾上腺素的反应性也部分恢复。
This paper particularly describes the mechanism of the organophosphorus pesticides detection , investigates the method of the acetylcholinesterase ( ache ) immobilized on the laps chip , and discusses how the ache film , the buffer and the acetylcholine substrate influence the performance of the sensor . finally the way of the preservation of the sensor is given , and the life of the sensor is estimated 论文详细的阐述了有机磷检测的基本原理，研究了乙酰胆碱酯酶( acetylcholinesterase , ache )在laps上的固定化方法，深入讨论了ache膜、缓冲溶液、乙酰胆碱底液对有机磷laps性能的影响，还给出传感器的保存方法及保存寿命。
Strain mrv and strain cvs are belong to the same genotype . however , strain mrv , ctn and cnx8511 are belong to different sub - genotype . finally , this researched also proved that the character of neuron tropism rabies viruses by comparison and analysis the homologies of amino acid sequence between 189 - 214 position and the bonding segment of snake venom curaremimetic neurotoxims and acetylcholine 从计算机建立的各毒株系统树分析， mrv和cvs属于一个基因亚型，和我国减毒株ctn以及人源野毒株cnx8511属于不同的亚型，并且证明了189 - 214位氨基酸序列与蛇神经毒素同乙酰胆碱结合部位的序列具有高度的同源性，说明狂犬病病毒的嗜神经特点。
In 1980 , furchgott and his colleagues presented the first evidence that acetylcholine ( ach ) , by acting on endothelial cells , stimulated the release of a relaxing factor ( edrf ) that acted on the preconstricted rabbit thoracic aorta to produce relaxation . a research interest on the endothelium - derived regulation of vascular tone , since then , is on the increase 自1980年furchgott发现乙酰胆碱( acetylcholine , ach )可通过内皮释放一种舒张因子( edrf ) ，使预先收缩的免主动脉环松弛以来，人们对内皮源性血管张力调节机制进行了广泛的研究，现已证实， edrf便是一氧化氮( no ) 。
