Based on the " self - migrating and surface - segregation " behavior , the amphiphile segregation surface was therefore constructed on hydrophobic pdl - la matrix , which containing the structure of peo spacer combining cell adhesion ligands to mimic the extracellular matrix ( ecm ) 基于两亲共聚物在疏水高聚物材料内的自迁移和表面富集行为，在聚乳酸材料上构建了以peo桥联氨基酸或整合素配体多肽片段的类细胞外基质表面。
Pathological studies have suggested that restenosis is mainly correlated to the vessel chronic elastic recoil , the thrombus formation in sites , the migration and proliferation of vascular smooth muscle cells ( vsmcs ) , and the excessive synthesis of extracellular matrix 研究认为，冠状动脉成形术后再狭窄的发生，主要与血管弹性回缩、损伤部位血栓形成、平滑肌细胞迁移和增生以及过量细胞外基质合成的关系最为密切。
Objective to investigate the effects of saikosaponind on glomerular mesangial cells proliferation and hyperplastic extracellular matrix induced by lipopolysaccharide to provide experimental proof for its use in prevention and tre . . 目的探讨柴胡皂苷d saikosaponin d , ssd对脂多糖lipopolysaccharides ， lps作用后肾小球系膜细胞mesangial cell ， mc增殖及细胞外基质extracellular matrix ， ecm的异常增生的影响，为肾小球
Laminin is not only the mainly structural molecule of extracellular matrix , but also the important signal molecule . laminin and collagen iv compose the net - structure of the extracellular matrix , given the tissue of elastic , tenacity , water - holding power , amortization of mechanical power , ect 层粘蛋白与型胶原蛋白构成网状的细胞外基质结构，赋予组织以韧性、弹性、保水性及对机械力的缓冲性，并为细胞提供生存及从事活动的微环境。
We identify , for the first time , a number of gene candidates that are induced by dht with or without ischemia , many of which could account for cell death through enhanced inflammation , dysregulation of blood - brain barrier and the extracellular matrix , apoptosis , and ionic imbalance 我们首次发现，许多候选基因在有无缺血时都由dht诱导，这其中的许多基因能够解释通过增加炎症、血脑屏障和细胞外基质失调、凋亡和离子失衡等原因产生的细胞死亡。
This strategy involved a concomitant induction of adipogenic differentiation whilst ascorbic acid supplementation stimulated the stromal cells to produce and organize their own “ biomaterial ” in the form of extracellular matrix , forming manipulatable sheets that are then assembled into thicker reconstructed adipose tissues 这种策略涉及成脂诱导去刺激间质细胞以细胞外基质的形式产生并组装他们自己的生物材料,形成可组装更厚脂肪组织的膜。
It is well known that various kinds of biological substances such as growth factors , cytokines and adhesion molecules are closely related with the wound healing process . in particular , adhesion molecules play an important role in the promotion of inflammatory reaction , these factors stimulate the synthesis of extracellular matrix by local fibroblasts , generate new blood vessels , promote the granulation tissue fonnation , and enhance re - epithelialization nthat takes places by the migration of the kerati - nocytes from the edges of the wound toward the center 多种生物学介质如：生长因子、细胞因子及粘附分子等与皮肤损伤愈合过程密切相关，尤为值得提出的是，粘附分子在炎症的发生的起始过程中起着至关重要的作用，这些因子在细胞外基质的形成、血管的发生、肉芽组织的生成及上皮的再形成方面等均具有重要作用。
Objective to investigate the effects of saikosaponind on glomerular mesangial cells proliferation and hyperplastic extracellular matrix induced by lipopolysaccharide to provide experimental proof for its use in prevention and treatment of glomerulosclerosis . methods wt5bzrats mcs were cultivated and identified 目的探讨柴胡皂苷d saikosaponin d , ssd对脂多糖lipopolysaccharides ， lps作用后肾小球系膜细胞mesangial cell ， mc增殖及细胞外基质extracellular matrix ， ecm的异常增生的影响，为肾小球硬化的防治提供实验依据。
