Development of high throughput microanalysis ( htma ) is proposed , which is a key issue in analytical chemistry and is essential to break through the bottle - neck emerged in life science since the outburst of post - genomic projects 本文讨论了微量水平的高通量分析问题，认为这是当前生命科学向分析化学所提出的最主要的挑战，也是分析化学发展必须解决的核心问题之一。
Development of high throughput microanalysis ( htma ) is proposed , which is a key issue in analytical chemistry and is essential to break through the bottle - neck emerged in life science since the outburst of post - genomic projects 摘要本文讨论了微量水平的高通量分析问题，认为这是当前生命科学向分析化学所提出的最主要的挑战，也是分析化学发展必须解决的核心问题之一。
Hd biosciences co . , ltd has announced an important research collaboration with organon , the human health care business of akzo nobel . the agreement relates to the development by hd biosciences of functional assays for a number of identified g - protein coupled receptors and ion channels 根据这项协议，华大天源将为欧加农公司构建一系列的g蛋白偶联受体家族和离子通道家族的筛选模型，这些筛选模型均适应于高通量药物筛选。
Development of high - throughput gene microarray as a new powerful technique has improved our understanding of the rheumatoid arthritis , and it has been successfully applied to study the inflamed paws of mice or rats systemically immunized with arthritogenic compounds to induce arthritis 摘要基因微阵列作为一种高通量的技术，是类风湿关节炎研究的一个新型的强有力的工具，已经被成功运用到几种不同方式诱导的小鼠或大鼠类风湿关节炎动物模型中。
Currently there are many techniques available to screen the gene expression at the transcriptional levels , such as mkna differential display and cdna microarray . although these methods can provide high - throughput information about the differential gene expression , they can 虽然，利用mrna差异显示技术和基因芯片技术可在转录水平高通量的筛选基因表达的差异，但是这些技术都不能提供转录后的尤其是蛋白质在翻译后修饰的信息，而蛋白质通常是细胞内的功能执行者。
On the one hand , the theoretics of drug discovery become more comprehensive and more profound as the development of numerous new disciplines such as genomics , proteomics , transcriptomics , metabonomics , bioinformatics and system biology ; on the other hand , the pathways for new drug discovery are broadened by the continuous improvement of technological platforms including computer - aided drug design , high throughput screening , high content screening , biochip , transgenic and rnai technology 一方面，基因组学、蛋白质组学、转录组学、代谢组学、生物信息学、系统生物学等新兴学科的崛起与发展，为药物发现提供更为广泛而深刻的理论基础；另一方面，计算机辅助药物设计、高通量筛选、高内涵筛选、生物芯片、转基因和rna干扰等高新技术的发展和完善，为药物发现提供了新的技术手段和有力工具，极大地拓宽了药物发现的途径。
The quickly developing techniques of biological mass spectrometry ( bio - ms ) in recent years realized the high throughput identification of proteins by determining the accurate mass values of trypsin - digested peptides and the randomly selected peptide sequence tags , and have been successfully used in the studies of protein interactions and post - translational modification such as the phosphorylation 摘要近几年快速发展起来的生物质谱技术，依靠（酶解后肽段）精确质量数测定和随机肽序列标签分析，实现了对蛋白质高通量的鉴定，并被成功地用于蛋白质相互作用和蛋白质磷酸化等翻译后修饰研究。
Besides , the centre actively seeks opportunities for the development of multi - disciplinary programmes to combine cutting edge research in molecular and cell biology , biochemistry , chemical biology , bioinformatics and clinical medicine , using advanced and high throughput genomic technologies . the centre is a participant of the international haplotype mapping project 此外，中心亦积极寻求发展跨学科研究的机会，藉著先进及高通量的基因技术，结合在分子及细胞生物学、生物化学、化学生物学、生物资讯学及临床医学方面的尖端研究。
The study conducted research on the following four fields : firstly , the characteristics of the interfacial polymerization system of piperazine aqueous solution / trimesoyl hexane solution were systematically investigated . the results show that at a certain molar ratio between the two monomers , piperazine and trimesoyl , at the two phase interface , a dense functional layer of ultra low pressure , high permeating flux and high salt rejection formed by controlling the time of interfacial polymerization , such as the composite membrane ( i ) , the concentration in water phase is 0 . 4 % , and 0 . 1 % in organic phase , and the polymerization time is 1 minute 本文主要进行了四个方面的研究，首先系统分析和研究了哌嗪水溶液均苯三甲酰氯正己烷溶液界面聚合体系特征、界面聚合反应中各影响因素对膜性能的影响等，结果发现，当界面处两相单体(哌嗪和酰氯)分子摩尔比为某一比值时，通过控制界面聚合时间(有机相处理时间) ，可以形成超低压高通量高脱盐的致密功能层，如复合膜( ) ，水相浓度为0 . 4 ，有机相浓度为0 . 1 ，聚合时间1min 。
