With the development of blood purification in the past sixty years , renal substitution therapy with hemodialysis or hemofiltration has been an important life - sustaining technology 经过60多年血液净化技术的发展历程，以血液透析、血液滤过为代表的肾脏替代治疗已显著改善了急慢性肾功能衰竭的预后。
Conclusion : routine therapy combined with jpqhr can significantly decrease blood lipid level and strengthen cellular immune system , so it can lower the urine protein in the early and middle stages of chronic renal failure and improve renal function 结论：早、中期慢性肾功能衰竭患者在常规治疗的基础上加用健脾清化方，能显著降低血脂，提高细胞免疫功能，从而改善肾功能，降低蛋白尿。
Conclusion : mitral and aortic valves were vulnerable to calcification which was the major change of heart valve in patients with crf on maintenance hemodialysis , the degree of calcification was closely related to hyperphosphoremia , secondary hyperparathyroidism and a longer period of hemodialysis 结论:慢性肾功能衰竭维持性血液透析患者心脏瓣膜病变均以钙化为主,尤以二尖瓣、主动脉瓣易发,且钙化程度与钙磷乘积、继发性甲状旁腺机能亢进和血液透析年限密切相关。
