The results showed that the expressions of il - 1 receptor type 6 tt i in normal adult rat brain were very widely , and there were intense immuno - positive cells of il - 1 receptor type i in septal area , medial preoptic area , neocortex , hippocampus , paraventricular nucleus of the hypothalamus , supraoptic nucleus , hypothalamic ventromedial nucleus , arcuate nucleus and median eminence 结果显示：型il - 1受体在正常成年大鼠脑内有广泛的表达，隔区、视前内侧区、新皮质、海马、下丘脑室旁核、视上核、下丘脑腹内侧核、弓状核和正中隆起等部位有较多型il - 1受体阳性的细胞。
After i . c . v . 6 - ohda , the c - fos expression of these areas induced by cold stress reduced significantly . 2 ) double staining showed that fos - like immunoreactive positive granules were observed in some vasopressin ( avp ) - immunoreactive positive neurons in paraventricular and supraoptic nuclei , as well as in some tyrosine hydroxylase ( th ) - immunoreactive positive neurons in nts and lc nuclei ( 2 )双重染色显示，寒冷应激诱导的fos样免疫反应阳性颗粒可见于室旁核( pvn )和视上核( son )中的部分加压素( avp )阳性神经元及孤束核( nts ) 、蓝斑( lc )中的部分酪氨酸羟化酶( th )阳性神经元。
The expressions of il - 1 receptor type i in mouse brain were widely distributed . and the expressions in mouse pvn and son were significantly enhanced by an intraperitoneal administration of lps or seb ( p < 0 . 05 or 0 . 01 ) . the arginine vasopressin - and oxytocin - containing neurons in the pvn and son also displayed immunofluo - rescence labeling for il - 1 receptor type i F0刀1 ） ； i型il 1受体在正常小鼠脑内的表达很广泛，与对照组比较， lps或seb引起1型几l受体在小鼠下丘脑室旁核和视上核中表达显著增强（ o
In this paper , we studied the deterministic mechanism of isi with the unstable period orbit ( upo ) ; we tested many isi data from different model with the method of approximate entropy ( apen ) to study the method which is used in testing the degree of complicacy of isi and we built up a system including hardware and software for our lab to view and record action potential , firing frequency and isi in real time . results 1 . spontaneous firing patterns were observed from neurons of supraoptic nucleus ( son ) in hypothalamus with the method of patch clamp 本研究通过对大鼠视上核神经元自发放电的非稳定周期轨道的计算，讨论了isi的确定性问题；利用近似熵的方法对多种神经放电的isi资料进行了复杂度的测量，讨论了这种方法在isi的复杂度测量第四军医大学硕士论文中的应用；另外，还开发出一套记录原始放电和isi的程序，解决了采集isi的问题。
