There are so many molecules involved the fertility , such as : spl7 , a mammalian testis - and sperm - specific protein , can specifically bind with zona pellucida , dextran , dextran sulfated , and fucoidin . another germ cell cyritestin is a testis - and sperm - specific protein belonging to the adam family . it has a disintegrin domain at the n - terminal , known as a integrin ligand , that suggests cyritestin could be involved in sperm adhesion and fusion with the egg membrane previous study demonstration 配子中的许多分子均参与了上述关键环节，如在精母细胞、精细胞和睾丸精子中表达，并特异性与卵子透明带糖蛋白、葡聚糖、糖酐脂结合的精子表面蛋白17 ( sp17 ) ，以及参与识别或与卵子膜上的整合素相互作用的adam家族成员之一的cyritestin蛋白等。
1 - . studies on the inhibition of angiogenic properties by monoclonal antibody against integrin endothelial cell adhesion and migration are important processes during angiogenesis . the capacity of endothelial cells to recognize and migrate in response to the extracellular matrix ( ecm ) depends on one or more members of the integrin family of cell adhesion receptors 血管新生的过程依赖于参与血管生成的细胞因子和细胞粘附的协同作用，整合素( integrin )是一组细胞表面受体，介导细胞-细胞间、细胞-基质间的相互作用，对内皮细胞的粘附、迁移、增殖起重要作用。
