The results were as follows : ( l ) the pre - incubation of pmr induced the exocytosis of the cortical granules ( cgs ) in the oocytes and reduced the quantity of the microvillus on the surface of oocytes ; ( 2 ) the matrix of cg might migrate to the surface of plasma membrane of oocytes after pmr pre - treatment . ( 3 ) incubation of zona - free hamster eggs with spermatozoa pretreated with pmr a ntiserum was associated with a dose - dependent significant reduction in the number of spermatozoa binding to the oolemma , compared with a contraband with a dose - dependent reduction of the fertilization rate and the penetration index . the results indicate that mr of human sperm plays an important role in sperm - oocyte fusion and oocyte activation 结果显示： ( 1 )人精子mr能够诱发去透明带金黄地鼠卵母细胞中皮质颗粒的胞吐，并引起卵母细胞膜表面微绒毛形态和数量发生改变； ( 2 )皮质颗粒胞吐后，其内容物可结合到卵膜表面； ( 3 )抗mr抗血清预处理精子可抑制精子与卵子的结合与融合，使受精率、穿透指数和结合指数下降，并均有剂量依赖性。以上结果提示，人精子mr在受精过程中起重要作用，其主要作用可能是介导精-卵膜融合并促进卵母细胞的活化。
Globally , this dramatic drop in fertility has occurred in past 10 years , with a general trend towards men suffering from an increasing number of sperm abnormalities like poor mobility , where sperm cannot swim to meet the egg or the sperm may acquire a wrong shape , making its penetration of egg ' s outer layer difficult 总体来说，生育能力的戏剧性下降10年来一直在发生，普遍伴随着弱活动度等异常精子数量的增加，造成精子不能泳动与卵子结合，或者异常形态使得精子难以穿透卵子的外层。
