There was a dose - dependent relationship between da release and the administered dosage of the drug . but the drug has showed no influence on da release from amy of male rats in 60min after injection 但两种浓度乌鸡白凤丸有效成分对雄鼠的amyda释放在注射后60min内均未表现增加作用。
The nymphae and ten - day old female adult were more sensitive to the fungal spores than the thirty - day old female adult , and both then - nhs decreased significantly after injection with 4 + 107 spores / ml 若虫和10日龄雌成虫对绿僵菌孢子比较敏感，注射4 10 ~ 7个/ ml浓度的孢子后其血细胞数量均降低显著，最低时分别为空白对照的4 . 6及8 . 5 。
Two donkeys were injected intravenously with the pd70344v stock and developed acute diseases at 9 day and 12 day after injection , respectively . one animal ( donkey 03008 ) was euthanized due to the severity of the clinical symptoms on day 17 after injection and the other donkey ( 03009 ) died on day 18 after injection . we observed high fever , weigh lost , anorexia , depression , thrombocytopenia and high plasma viremia levels during the courses 两头驴（编号03008和03009 ）分别在接种后第9天和第14天体温升高40ac以上，稽留数日，产生急性病毒血症，其中一头于发热后期实施迫杀，另一头驴在第一次发热后自然死亡，病原学和病理学检查判定为急性马传贫。
1 . physical changes of hemolymph of p . americanna after injection with m . anisopliae the ph value of hemolymph of p . americanna increased rapidly from ph6 . 8 to ph 7 . 0 and the number of hemocytes ( nh ) of p . americanna at all the developing stages became lower than the blank control ( bc ) after injection with 4 + 107 / ml fungal spores 1注射绿僵菌孢子后蜚蠊血淋巴物理性质的变化蜚蠊若虫血淋巴ph值为ph6 . 8 ，注射4 10 ~ 7个/ ml浓度的绿僵菌孢子到蜚蠊体内后，蜚蠊血淋巴的ph值上升到ph7 . 2 。
Peripheral blood ( pb ) was collected 2 > 4 > 8 weeks after injection . facs was used to quantity human cells in the rat pb , pcr and immunohistochemisty were used to detect human cells in the pb as well as in other tissues , such as liver , spleen , pancreas , kidney , et al 1周、 2周、 4周、 8周后取新生大鼠的尾静脉血，提取基因组dna ， pcr检测人特异性_ 2微球蛋白基因序列片段；流式细胞仪检测外周血中人源cd45 ~ +细胞的比例；免疫组化检测大鼠组织中人源细胞的多向分化。
3 antimicrobiol substance and protein in the hemolymph of nymphae induced by m . anisopliae no antimicrobiol substance was detected in the hemolymph of nymphae by different kinds of micropathogens after injection with m . anisopliae , which meant that the fungus could not induce p . americanna to produce antimicrobiol substance . injection of fungal spores caused the decline of protein concentration ( pc ) at the begaining , but after that the pc increased rapidly 3绿僵菌孢子对蜚蠊血淋巴中抗菌物质及蛋白质的诱导注射绿僵菌后的不同时期提取蜚蠊血淋巴，以多种不同类型的植物病原菌、昆虫病原菌及腐生菌作为检测菌，均未检测出蜚蠊血淋巴中有抗菌物质存在，即绿僵菌不能诱导蜚蠊产生抗菌物质。
Among these callers 353 said that they had approached medical centres which were involved in the incident for flu vaccination . eighteen of them claimed there was no severe adverse effect after injection but had minor reactions like low grade fever , redness and swelling at the injection site 此外?生署热线至今共接获642个查询电话，其中353人声称曾分别在涉及事件的医疗团体或诊所接受流感疫苗注射。 18人称于接受注射后有轻微反应包括低烧，针口附近红肿，但无严重不良反应。
Studies of the crystal structure of endostatin have shown a compact globular fold , with one face particularly rich in arginine residues acting as a heparin - binding epitope , this site was recently shown to be involved in the inhibition of induced angiogenesis . experimental studies show that recombinant endostatin specifically inhibits the proliferation of endothelial cells in a dosedependent fashion . recombinant endostatin from bacteria is largely insoluble , but still efficient in arresting tu mor growth after injection into mice . intermittent therapy with recombinant bacterially produced endostatin reduces several experimental tumors , including lewis lung carcinoma , to a dormant state . no sign of drug induced resistance has been reported and , in the original study , the treatment dormancy appeared to persist even when therapy was discontinued . sowe regard endostatin as a promising anti - tumor drug 许多研究表明重组内皮抑素特异性抑制内皮细胞增殖，而且这种抑制作用呈剂量依赖性。细菌表达产物内皮抑素大部分以不溶形式存在，将这种混悬液注射治疗老鼠仍可以抑制肿瘤生长。于小鼠皮下重复注射内皮抑素重组蛋白，几乎完全抑制鼠lewis肺癌等多种肿瘤生长，并无耐药性产生，即使中断治疗肿瘤也不再复发。
