" this development is a significant setback for our company , our shareholders , our players and our industry , " said mitch garber , partygaming ' s ceo 派对赌博的执行长米契加柏说：这项发展对我们的公司、股东、玩家及整个行业都是一大打击。
The withdrawal is a big blow for merck , which is already reeling from the failure of two of its most important new medicines in clinical trials 撤回罗非考昔对默克是一个沉重打击。此前，该公司两种最重要的新药在临床试验中失败，已令公司受到很大打击。
Strengthening greater boston s economy : a record of achievement south boston waterfront plan approved a zoning plan that will create a world - class neighborhood on the south boston waterfront has been approved by state regulators 1963年11月盟日肯尼迪遇刺身亡，给波士顿财团一大打击，使它在同其他财团的竞争中地位不断下降。
The recent outbreak of avian influenza in a number of places in east asia has undoubtedly cast a shadow over the regional economic situation . but with the support of a generally upbeat outlook for exports , avian influenza is not expected to pose a serious threat to the regional economy 东亚地区方面，多个国家及地区近期爆发禽流感，令区内经济蒙上一些阴影，但在出口前景普遍仍然乐观之下，相信禽流感不会对区内整体经济造成很大打击。
The recent outbreak of avian influenza in a number of places in east asia has undoubtedly cast a shadow over the regional economic situation . but with the support of a generally upbeat outlook for exports , avian influenza is not expected to pose a serious threat to the regional economy 东亚地区方面，多个国家及地区近期爆发禽流感，令区内经济蒙上一些阴影，但在出口前景普遍仍然乐观之下，相信禽流感不会对区内整体经济造成很大打击。
