oncogenes,abl 《英文msh词典》Oncogenes,abl ; [入口词] Oncogenes,abl ; [主题词] Genes,abl ; [英文释义] Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
oncogenes,bcr-v-abl 《英文msh词典》Oncogenes,bcr-v-abl ; [入口词] Oncogenes,bcr-v-abl ; [主题词] Genes,abl ; [英文释义] Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
oncogenes,jun 《英文msh词典》Oncogenes,jun ; [入口词] Oncogenes,jun ; [主题词] Genes,jun ; [英文释义] Retrovirus-associated DNA sequences (jun) originally isolated from the avian sarcoma virus 17 (ASV 17). The proto-oncogene jun (c-jun) codes for a nuclear protein which is involved in growth-related transcriptional control. Insertion of c-jun into ASV-17 or the constitutive expression of the c-jun protein produces tumorgenicity. The human c-jun gene is located at 1p31-32 on the short arm of chromosome 1.
oncogene,v-src 《英文msh词典》Oncogene,v-src ; [入口词] Oncogene,v-src ; [主题词] Genes,src ; [英文释义] Retrovirus-associated DNA sequences (src) originally isolated from the Rous sarcoma virus (RSV). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20.
oncogenes,mos 《英文msh词典》Oncogenes,mos ; [入口词] Oncogenes,mos ; [主题词] Genes,mos ; [英文释义] Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c-mos can become transformed or has a role in human cancer. However,in mice,activation can occur when the retrovirus-like intracisternal A-particle inserts itself near the c-mos sequence. The human c-mos gene is located at 8q22 on the long arm of chromosome 8.
oncogene,v-sis 《英文msh词典》Oncogene,v-sis ; [入口词] Oncogene,v-sis ; [主题词] Genes,sis ; [英文释义] Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
oncogenes,myb 《英文msh词典》Oncogenes,myb ; [入口词] Oncogenes,myb ; [主题词] Genes,myb ; [英文释义] Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts,Dictionary of Cytokines,1995).
oncogene,v-rel 《英文msh词典》Oncogene,v-rel ; [入口词] Oncogene,v-rel ; [主题词] Genes,rel ; [英文释义] Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
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oncogenes and growth factors abstracts 肿瘤学及生长因素文摘
"for their discovery of the cellular origin of retroviral oncogenes 发现逆转录病毒原癌基因oncogene在细胞中的产生
C-myc oncogene overexpression in endometrial cancers and its clinicopathological characteristics 癌基因的表达及临床意义
Established that proto-oncogenes play important roles in normal cellular control 确立原癌基因在正常细胞调控中的重要作用
oncogene related gene 癌,基因相关基因
The expression of oncogenes in hel cells treated with cigarette smoking and asbestos 吸烟与石棉对人胚肺细胞某些癌基因表达的影响
Expression of oncogene correlates with survival rate and survival quality in osteosarcma 癌基因表达对骨肉瘤患者生存率及生活质量的意义
Expressive characteristic and biological significance of oncogenes during rat hepatocarcinogenesis 大鼠肝癌形成过程中癌基因表达变化的意义
If several oncogenes are driven into action, the cell, unable to turn them off, becomes cancerous 如果若干癌基因被激活,细胞无力排除也就演变成了癌细胞。
Effect of weiyankang plus gastrone on expression of oncogene proteins in gastric mucosa with precancerosis lesion 胃炎康加维酶素对胃癌前病变胃黏膜癌基因蛋白表达的影响