?e did not influence the spontaneous mepsc in sg . however, after pretreatment with ne, the facilitatory effect of capsaicin on neurotransmitter release from primary afferent terminals was significantly depressed ne对sg内自发的ilepscs无影响,但在ne预灌流后,caps增强初级传入终末神经递质释放的程度显著降低。
?he pretreatment of ne together with yohimbine, an a, adrenergic receptor antagonist, had no effect on the facilitatory action of capsaicin on neurotransmitter release from primary afferent terminals . this result suggests that the a2 adrenergic receptor on primary afferent terminals might be involved in ne depression on capsaicin-induced neurotransmitter release 将飞型肾上腺素受体阻滞剂育亨宾(yohimbine)与ne同时预灌流后,caps对初级传入终末递质释放的易化作用不受影响,提示初级传入纤维终末上的a。